Effect of nifedipine on exercise tolerance in angina pectoris.
نویسندگان
چکیده
منابع مشابه
Effect of nifedipine on exercise tolerance in angina pectoris.
Nifedipine is a new antianginal drug, the calcium-antagonistic inhibitory action on excitation-contraction coupling apparently being so pronounced that, in therapeutic dosage, all other pharmacological properties are negligible. Its effect on exercise tolerance in angina was assessed by an exercise study involving 14 patients: single-stage exercise tests were chosen and the advantages of this a...
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-Our objective was to compare cardiovascular event rates in patients with stable angina receiving nifedipine as monotherapy or combination therapy and in active drug controls. A MEDLARS search of published articles from 1966 to 1995 in English, French, German, Italian, or Spanish, supplemented by a manual search of bibliographies, identified 60 randomized controlled trials that met protocol cri...
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A patient had accelerated attacks of chest pain associated with transient ST elevation or depression in the anterior leads. Coronary angiogram revealed severe multi-vessel disease. Anginal attacks with conspicuous ST depression were induced repeatedly by both oral and sublingual administration of nifedipine. Among various vasodilator drugs tested on this patient, dipyridamole and hydralazine in...
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OBJECTIVE EVIDENCES for angina pectoris, in the absence of proved myocardial infarction or grossly abnormal electrocardiograms, are more or less limited to abnormal electrocardiographic changes induced by exercise or hypoxemia. Similarly, while termination or prevention of angina is notoriously unreliable in the evaluation of "coronary dilator" drugs, their effects on provoked abnormalities in ...
متن کاملAdaptation to exercise in angina pectoris.
PATIENTS with angina pectoris due to coronary artery disease may have great variability in exercise tolerance. In some this variability fits a pattern wherein increased exercise tolerance is dependent on a preceding episode of exercise-induced angina pectoris. The most complete expression of this phenomenon may be in the patient who is able to overcome an attack of angina pectoris by persisting...
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ژورنال
عنوان ژورنال: Heart
سال: 1980
ISSN: 1355-6037
DOI: 10.1136/hrt.44.3.335